Anti-Diabetic Activity And Anti-Oxidant Activity Of Kalanchoe Pinnata And Their Characterization Studies.

Abstract

Species of Kalanchoe have been used as a remedy for various infectious diseases and cancer treatment. This study evaluates the anti-diabetic properties of the plant, Kalanchoe pinnata. Phytochemical components, anti-oxidant assays were also carried out. Phytochemical analysis showed the presence of alkaloids, flavonoids, steroids, phenolic compounds. The free radical scavenging activity was determined in which the ethanol extract showed the maximum inhibitory effect when compared with aqueous extract .Thin layer chromatography was done to determine the compound in a solvent system of methanol, acetic acid, formic acid and water in the ratio 3:1:1:0.5 . Characterization of the leaf extract was done by UV-visible spectroscopy which showed the peak between 300-350nm. FTIR analysis showed the presence of the various functional group present in the plant. Aqueous and ethanol extract was subjected to α-amylase inhibitory effect and α-glucosidase inhibitory effect to find the antidiabetic potential activity of the plant extract.

Key words: Kalanchoe, Phytochemical, Antidiabetic, TLC, Antioxidant